Paracetamol, also known as acetaminophen, is a medication used to treat pain and fever. It is typically used for mild to moderate pain relief. Evidence is mixed for its use to relieve fever in children. It is often sold in combination with other medications, such as in many cold medications.
Class – Antipyretic & Analgesic
Syrup – 120mg/5ml, 125mg/5ml
Drops. – 100mg/1ml
Mechanism Of Action
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors.
Children – Min Dose – 10 – 15mg/kg/dose 4-5 doses if needed. Not to exceed 5 dose in 24 hours.
Max Dose – 75mg/kg/day and not to exceed 4g/day
Used As- Fever, Pain
Contraindicated – Safe in Pregnancy